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Inganda zitanga Cilengitide 98% ifu yera CAS NO.188968-51-6

Cilengitide CAS OYA: 188968-51-6
Cilengitide ni peptide ya cyclic pentapeptide irushanwa kuri peptide ya arginine-glycine-aspartate (RGD).Igenga integrin-ligand guhuza.Cilengitide ihitamo kandi ibuza alpha v beta 3 beta na alpha v 5 integrin ihujwe na proteine ​​za matrix, nka Vitronectin, Fibronectin, Fibrinogen, vonWillebrandFactor, Osteopontin, nibindi.10μMCilengiChemicalbooktide irabuza rwose guhuza ingirabuzimafatizo za BAE, BME na HUVE kuri Vitronectin na Fibronectin.C.Cilengitide ibuza ikwirakwizwa ry'utugingo ngengabuzima, itera selile apoptose ya endoteliyale, kandi itera endothelial precursor selile itandukanye.


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izina RY'IGICURUZWA Cilengitide
URUBANZA 188968-51-6
Inzira ya molekile C27H40N8O7
uburemere bwa molekile 588.66
ubucucike 1.41 ± 0.1 g / cm3 (Biteganijwe)
gukemura ≥29.43 mg / mL muri DMSO;≥22.56 mg / mL muri H2O
Coefficient ya acide (pKa) 4.01 ± 0.10 (Biteganijwe)
Kugena (1)
Kugena (1)
Kugena (2)

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