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Imiti yubushakashatsi bwimiti Etelcalcetide Ifu yera CAS NO.1262780-97-1

Izina RY'IGICURUZWA: Etelcalcetide
URUBANZA: 1262780-97-1
uburemere bwa molekile: 1048.25
amata ya molekile: C38H73N21O10S2
ubucucike: 1.58 ± 0.1 g / cm3 (Biteganijwe)
gukemura Gukemura muri DMSO
Coefficient ya acide (pKa) 2.01 ± 0.10 (Byahanuwe)

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Etelcalcetide CAS OYA: 1262780-97-1
Etelcalcetide ni igitabo cyitwa CalcimimeticAgent, gitangwa mu mitsi kandi cyakozwe ku barwayi b'impyiko zidakira (CKD) barwaye hemodialyse.AMG416 ihuza kandi igakora reseptor yunvikana ya calcium kuri glande ya parathiyide, bigatuma igabanuka rya hormone ya parathiyide (PTH).FDA yemeje calcium nshya imeze nka agent veracartide yo kuvura hyperparathyideyide ya kabiri ku barwayi bakuze ba hémodialyse, imiti ya mbere yemerewe kuvura hyperparathiyide ya kabiri mu barwayi ba dialyse mu myaka 12.Ku barwayi bafite hyperparathyide idakabije kandi ikabije ivurwa na hemodialyse, urwego rwa PTH rwaragabanutse cyane.

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