Ibikoresho bibisi Thymosine Beta 4 TB500 / TB-500 agace ka 885340-08-9

TB500 ni molekile ya sintetike mukarere gakomeye ka thymosine beta 4. TB500 iteza imbere ingirabuzimafatizo ya endoteliyale, angiogenezi mumyanya ya dermis, kwimuka kwakagari, kubika kolagen no kugabanya umuriro.Sobanura angiogenezi (ANG), proteine ​​14,124 Da ifitanye isano na angiogenez mugukomeza kubyimba.Irekurwa na selile yibibyimba, bigira uruhare runini mu gukora imiyoboro mishya y'amaraso.
Ibiranga imiterere Acharya n'abandi.yagennye imiterere ya kristu ya antigene yabantu kuri 2.4 0 A. Imiterere rusange ifite impyiko eshatu zimeze nkimpyiko zibutsa RNaseA.Ikigo cyibikorwa bya RNA lysis (His-13, His-114 na Lys-40) hamwe na hypothetical reseptor ihuza ibibanza, ibikorwa bibiri byingenzi bigira uruhare mubinyabuzima bitandukanye na Rnase A 5. Intangiriro yo hagati ya molekile igizwe na P- ibyubaka hamwe no kugoreka anti-parallel, bigize topologiya nyamukuru, hamwe na base-Ser-72 isigaye na Gly-99 kuri vertices.Imiterere nyamukuru yuzuye yuzuzwa n'iminyururu ibiri yinyongera kumpande zombi zurunigi rwagati (ibisigaye 41-47; 111-116).Hano hari 3 helix H1, ibisigaye 3-14, H2, ibisigaye 22-33 na H3, nibisigaye 49-58.